Early-onset Alzheimer’s: Causes? How common is it? How does it progress?
What causes it?
This is purely genetics. Many people with early onset Alzheimer’s
had parents or loved ones who experienced the disease early on. Three
particular genes have been directly linked to early onset Alzheimer’s. They are:
APP, PSEN 1 or PSEN 2. If these genes are present within a spinal fluid sample
individuals have a very high risk of developing the disease early on versus
those who don’t have these genes present. The genetic mutation has a stronger rate
of inheritance once these three genes show mutations, researches are trying to
find other causes, some speculate that environment, diet, and lifestyle all
play roles in how symptoms progress.
How common is early-onset Alzheimer’s?
The percentage of people suffering with early onset Alzheimer’s disease
is very low, only 5 percent of the total Alzheimer’s patients will develop symptoms
before the age of 65. Of the American population, 15 million will have Alzheimer’s
of that 750,000 will be diagnosed with early onset Alzheimer’s. Due to its
rarity it is commonly misdiagnosed. The earliest age that has been affected by
this disease is people in their 30’s, the number of people in this category is
less than a fraction of a percent, making finding care, information, or
treatment difficult due to awareness. More often than not, people will
experience the disease in their 50’s, this is still considered early because
the vast majority will be affected after their 65 birthday.
Does it progress at a faster rate?
This isn’t a true fact. The perception is that it does progress
faster only because those who have it tend to be of younger age. They tend to
still have children that live with them; they have careers and
responsibilities, and maybe even elderly parents to take care of.
Since these factors may be present, individuals suffering from
early onset Alzheimer’s may require greater care, forcing spouses and loved
ones to seek in home care or even sending these individuals to an elder care
facility, so they could better cope with this disease.
If early-onset Alzheimer’s runs in my family, should I get tested for it?
If your family does have a history of the disease, taking the
time to evaluate your risk may be necessary depending on your current situation.
This decision is totally up to you! .Although, asses your risk may help you
plan for arrangements once the disease progresses, your family and loved ones
may have options to support your day to day care or to find a speciality service.
As well, finding out may hinder your ability to apply for life insurance, long
term care facilities, and even disability insurance. These types of factors
must be considered before deciding whether or not you should be tested for the
disease.